Effects on the Human Body:

Mechanism of Action: Kratom’s active compounds, mitragynine and 7-hydroxymitragynine, interact with opioid receptors in the brain, producing effects ranging from pain relief to mood modulation.

Stimulant vs. Sedative: At low doses (<5gr), kratom acts as a stimulant, boosting energy and alertness. At higher doses (5 – 15gr), it has sedative effects, providing pain relief and euphoria.

Other Neurotransmitter Systems: Kratom also affects adrenergic and dopaminergic pathways, contributing to its diverse range of effects.